Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Empathic Traits Modulate Oscillatory Dynamics Revealed by Time-Frequency Analysis During Body Language Reading. [PDF]
Brain SciProverbio AM, Scognamiglio P.
europepmc +1 more source
Oil price shocks and the term structure of the US yield curve: a time-frequency analysis of spillovers and risk transmission. [PDF]
Ann Oper Res, 2022 Umar Z +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Time-frequency analysis and autoencoder approach for network traffic anomaly detection. [PDF]
MethodsXPurohit R, Kumar S, Sayyad S, Kotecha K.
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
DEP-CEEMDAN-MPE-INHT a time-frequency analysis method for noisy blasting seismic waves with adaptive noise suppression and endpoint processing. [PDF]
Sci RepSun M, Wu J, Wang YF, Lu YN, Yu FD.
europepmc +1 more source
Public attention, oil and gold markets during the COVID-19: Evidence from time-frequency analysis. [PDF]
Resour Policy, 2022 Li S, Xu Q, Lv Y, Yuan D.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Time frequency analysis of elastic wave PSO OMP for defects in flat steel of down conductors. [PDF]
Sci RepZhang J +5 more
europepmc +1 more source