Results 81 to 90 of about 1,030,905 (215)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Analyzing Systemic Risk Spillover Networks Through a Time-Frequency Approach
MathematicsThis paper investigates the spillover effects and transmission networks of systemic risk within China’s national economic sectors under extreme conditions from both time and frequency domain perspectives, building upon the spillover index methodology and
Liping Zheng +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Research on Coal Gangue Recognition Based on Multi-source Time-Frequency Domain Feature Fusion. [PDF]
ACS Omega, 2023 Zhang Y, Yang Y, Zeng Q.
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Revista Colombiana de Estadística, 2009 Two methods of dimensionality reduction of multivariate stationary time series are analyzed: Peña-Box’s methodology in the time domain and Brillinger’s methodology in the frequency domain.
Zhang Hanwen
doaj
Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots
Veterinární MedicínaHeart rate variability analyses using Poincaré plots can be useful for evaluating the autonomic nervous system function. However, the interpretation of the quantitative indicators of Poincaré plots remains controversial.
T Kimura +8 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Comparación entre dos métodos de reducción de dimensionalidad en series de tiempo
Revista Colombiana de Estadística, 2009 En este trabajo se analizan dos métodos de reducción de dimensionalidad en series de tiempo multivariadas estacionarias: el método de Peña y Box, basado en el dominio del tiempo, y el método de Brillinger, basado en el dominio de las frecuencias.
HANWEN ZHANG
doaj
Global energy markets connectedness: evidence from time-frequency domain. [PDF]
Environ Sci Pollut Res Int, 2023 Rehman MU, Naeem MA, Ahmad N, Vo XV.
europepmc +1 more source