Results 81 to 90 of about 2,570,440 (302)

High intensity, short duration pulling in heavy horses: physiological effects of competition and rapid weight change

BMC Veterinary Research, 2017
Background The Heavy Horse Pull is a competition where teams of two horses pull an increasingly heavy sled for a short distance. Similar to human wrestlers, some horses may undergo rapid weight change in order to enter a lower weight category.
Persephone Greco-Otto, Shannon Massie, Erin Shields, Marie-France Roy, Edmond Pajor, Renaud Léguillette   +5 more
doaj   +1 more source

Does Hospital Competition Improve Efficiency? An Analysis of the Recent Market-Based Reforms to the English NHS [PDF]

This paper uses a difference-in-difference estimator to test whether the introduction of patient choice and hospital competition in the English NHS in January 2006 has prompted hospitals to become more efficient.
Alistair McGuire, Simon Jones, Steve Gibbons, Zack Cooper   +3 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

A new approach to measuring competition in the loan markets of the euro area [PDF]

This paper is the first that applies a new measure of competition, the Boone indicator, to the banking industry. This approach is able to measure competition of bank market segments, such as the loan market, whereas many well-known measures of ...
Bikker, Jacob A., Kok, Christoffer, van Leuvensteijn, Michiel, Van Rixtel, Adrian   +3 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Establishment and application of an AI-based network analysis model for enterprise market competition

Frontiers in Physics
Traditional market competition analysis methods struggle to capture complex competitive and cooperative relationships between enterprises. To address this, this study constructs an AI-based network analysis model for enterprise market competition. First,
Juan Li, Chunrong Sui
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Quantification of competition dynamics in multispecies systems using landscape and flux theory

Physical Review Research
Multispecies competition models contribute to understanding how various species interact in natural ecosystems and how these interactions influence population dynamics and ecosystem stability. However, achieving a comprehensive and physical understanding
Linqi Wang, Kun Zhang, Jin Wang
doaj   +1 more source

Hochschulpolitik als Komplement von Wettbewerbspolitik. Education Policy as a Complement Competition Policy

Eesti Majanduspoliitilised Väitlused, 2014
The current economic development in europe is a continuous cause for concern. First and foremoust in terms of the dept crisis, having a closer view regarding disbalances of competitiveness.
Jörg Dötsch
doaj   +1 more source

Retail Electricity Competition [PDF]

We analyze a number of unstudied aspects of retail electricity competition. We first explore the implications of load profiling of consumers whose traditional meters do not allow for measurement of their real time consumption, when consumers are ...
Jean Tirole, Paul L. Joskow
core