Results 111 to 120 of about 1,297,153 (289)

Multi-Switching Combination Synchronization of Three Fractional-Order Delayed Systems

open access: yesApplied Sciences, 2019
Multi-switching combination synchronization of three fractional-order delayed systems is investigated. This is a generalization of previous multi-switching combination synchronization of fractional-order systems by introducing time-delays.
Bo Li, Yun Wang, Xiaobing Zhou
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Apple Leaf Disease Recognition Based on Optoelectronic Time-Delay Reservoir Computing

open access: yesIEEE Access
The performance of an optoelectronic reservoir computing (RC) system for recognizing apple leaf diseases is numerically investigated. The disease spot feature extraction and selection methods suitable for time-delay RC are investigated.
Yushuang Hou   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Robust H Fault Tolerant Control on Suspension System of Maglev Train with Delayed Input

open access: yes机车电传动, 2012
Taking into account of the input time-delay, mathematical model of the suspension system was established for single suspension module of maglev train. Based on state feedback and LMI approaches, robust H fault tolerant controller was designed under the ...
严伟, 滕青芳, 范多旺
doaj  

Selected time delay data, phase 3 [PDF]

open access: yes
The results of a study on time delays in communication systems applicable to the teleoperator program are presented. Time delay data for 11 specific orbits of interest are shown.
Walsh, J. R., Wetherington, R. D.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

TIME-DELAY SYSTEMS [PDF]

open access: yes, 2010
Sun Yi, Patrick W Nelson, A Galip Ulsoy
openaire   +2 more sources

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