Results 111 to 120 of about 18,891,715 (293)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Lens Alternatives to Microscope Objectives in Optical Coherence Microscopy for Ultra-High-Resolution Imaging

open access: yesPhotonics
Ultrahigh lateral resolution (UHLR) optical coherence tomography (OCT) technology, also called optical coherence microscopy (OCM), has gained popularity, especially in the field of biomedical imaging.
Xinjie Zhu   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots

open access: yesVeterinární Medicína
Heart rate variability analyses using Poincaré plots can be useful for evaluating the autonomic nervous system function. However, the interpretation of the quantitative indicators of Poincaré plots remains controversial.
T Kimura   +8 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Identification of Moving Vehicle Loads on Bridges using Time Domain Method and Frequency-Time Domain Method (in Chinese)

open access: yes, 2001
Based on the Euler-Beam theory, the moving vehicle loads on bridges were identified from the response of bridges using the Time Domain MethQd (TDM) and Frequency-Time Domain Method (FTDM).
Chan, Tommy H.T., Yu, Ling, Law, S.S.
core  

A practical method for the detection of freezing of gait in patients with Parkinson’s disease

open access: yesClinical Interventions in Aging, 2014
Yuri Kwon,1 Sang Hoon Park,1 Ji-Won Kim,1 Yeji Ho,1 Hyeong-Min Jeon,1 Min-Jung Bang,1 Gu-In Jung,1 Seon-Min Lee,3 Gwang-Moon Eom,1,2 Seong-Beom Koh,3 Jeong-Whan Lee,1,2 Heung Seok Jeon41Biomedical Engineering, 2Research Institute of Biomedical ...
Kwon Y   +11 more
doaj  

Measuring Online Battery AC Resistance Using a DC-DC Converter With Time and Frequency Hybrid Method

open access: yesIEEE Access
The estimation of battery state is important for ensuring the stability of batteries. The AC resistance of a battery is one of the factors used to estimate the battery state, and is measured using a Fast Fourier Transform (FFT), a technique that analyzes
Seong-Jong Kim   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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