Results 71 to 80 of about 4,622,355 (269)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Design and System Characterization of Ultra-Wideband Antennas With Multiple Band-Rejection

IEEE Access, 2017
This paper presents system modelling and characterization of multiple-band notched ultrawideband (UWB) antennas using the singularity expansion method (SEM).
Sajjad ur Rehman, Majeed A. S. Alkanhal
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Time to Frequency Domain Analysis of Narrow Band Antennas

International Journal of Antennas and Propagation, 2017
This paper presents system modeling of three different single band antennas using the singularity expansion method (SEM). To acquire the accurate physical complex poles and the corresponding residues of the narrow band antenna model, an enhanced Matrix ...
Sajjad Ur Rehman, Majeed A. S. Alkanhal
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Analysis of the impact of leaks and valve maneuvers on pressure transient data in water distribution networks [PDF]

RBRH
Swift detection and repair of leaks in water distribution networks are essential to ensure the operational efficiency of the system. It’s not viable, both financially and technically, to scour the entire extension of the system to look for leaks ...
Matheus Sant’Anna, Rui Gabriel Souza, Guilherme Prudente, Bruno Brentan, Gustavo Meirelles   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Time Domain Subdivision Method for Optical Grating Signal Based on Time Series Analysis

Nanotechnology and Precision Engineering, 2018
Aiming at the restriction of the Moire signal quality on the subdivision multiple and accuracy, a time domain subdivision method for optical grating signals based on time series analysis is proposed.
Wang Baozhu, Li Wenjuan, Peng Kai, Wang Qiang, Li Meili   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time-Domain Analysis of Resonator Array Buffers [PDF]

IEEE Photonics Technology Letters, 2009
We present design and time-domain simulations of microresonator array optical delay lines. The proposed buffer consists of an n times m microresonator array unidirectionally coupled via a straight bus waveguide. We show that the use of a two-dimensional arrangement of resonators can compensate for the high order of dispersion and more specifically the ...
openaire   +1 more source