Results 101 to 110 of about 4,499,288 (288)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

WVD‐GAN: A Wigner‐Ville distribution enhancement method based on generative adversarial network

IET Radar, Sonar & Navigation
Time‐frequency analysis based on Wigner‐Ville distribution (WVD) plays a significant role in analysing non‐stationary signals, but it is susceptible to interference from cross‐terms (CTs) for multi‐component signals.
Daying Quan, Feitao Ren, Xiaofeng Wang, Mengdao Xing, Ning Jin, Dongping Zhang   +5 more
doaj   +1 more source

Experimental study on time-frequency characteristics of self-excited pulsed jet striking force in self-absorbing annular-air fluid type

Meitan kexue jishu
In order to quantitatively analyze the striking force of self-absorbing annular-air fluidic self-excited pulsed jet, and to improve the impact performance of downward-facing orifice submerged water jets, a high-frequency striking force test system of ...
Weiqin ZUO, Shengjie WU, Yanwei LIU, Liqun LONG, Haojie JIA, Jian MIAO, Shixi ZHANG   +6 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Approximation of the Wigner Distribution for Dynamical Systems Governed by Differential Equations

EURASIP Journal on Advances in Signal Processing, 2002
A conceptually new approximation method to study the time-frequency properties of dynamical systems characterized by linear ordinary differential equations is presented.
Cohen Leon, Galleani Lorenzo
doaj   +1 more source

Experimental optical fiber communications link [PDF]

An optical fiber communications link 1.5 kilometers in length was installed between the Interim Frequency Standard Test Facility and the Timing and Frequency Systems Research Laboratory at JPL. It is being used to develop optical fiber technology for use
Lutes, G. F.
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

DETERMINATION OF THE COEFFICIENTS OF A RATIONAL ANALYZING FUNCTION USING THE METHOD OF LEAST SQUARES

Измерение, мониторинг, управление, контроль
Background. This research relates to the field of aircraft location using electrostatic reconnaissance equipment. For digital processing of non-stationary electrostatic sensor signals of the system in question, convolution from the analyzing function ...
Yuriy M. Skryabin
doaj   +1 more source

Interpretable Evaluation of Sparse Time–Frequency Distributions: 2D Metric Based on Instantaneous Frequency and Group Delay Analysis

Mathematics
Compressive sensing in the ambiguity domain offers an efficient method for reconstructing high-quality time–frequency distributions (TFDs) across diverse signals.
Vedran Jurdana
doaj   +1 more source