Results 61 to 70 of about 2,232,503 (310)
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
wiley +1 more source
In the radar array signal processing direction of arrival (DOA), the estimation of weak non-stationary signal is an important and difficult problem when both strong and weak signals are coexisting particularly because the weak non-stationary signals are ...
Shuai Shao +5 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Reduced bias time-frequency peak filtering
Time-frequency peak filtering (TFPF) allows the reconstruction of signals from observations corrupted by additive noise by encoding the noisy signal as the instantaneous frequency (IF) of an FM analytic signal.
Boashash, Boualem, Mesbah, Mostefa
core +1 more source
Characterising the human-structure interaction effect of the Olympic Stadium in Cali, Colombia
This paper presents the results of analysing the human-structure interaction effect of the Olympic Stadium in Cali, Colombia. Acceleration in the southern and western grandstands due to ambient vibration, free vibration and forced vibration tests were ...
Albert Ricardo Ortiz +2 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The newly proposed Generalized Normal Distribution Optimization (GNDO) algorithm is used to design the truss structures with optimal weight. All trusses optimized have frequency constraints, which make them very challenging optimization problems. A large
Mirjalili, S, Khodadadi, N
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

