Results 111 to 120 of about 6,954,643 (310)

Reconstructing the Star Formation History of the Galaxy

, 2000
The evolution of the star formation rate in the Galaxy is one of the key ingredients quantifying the formation and determining the chemical and luminosity evolution of galaxies.
CC Lin, E Chereul, EC Vazquez, LH Amaral, P Saha, R Asiain, VS Avedisova, YN Mishkurov   +7 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Comparative Study of the Seismic Response of a Hotel Building With and Without Viscous Fluid Dampers

Buildings
Seismic design methods often involve high construction costs and may lead to severe structural damage during strong earthquakes. Energy dissipation technology represents an efficient approach to improving seismic performance through the integration of ...
Ariana Rodríguez, Jefferson Rodríguez, Marlon Farfán-Córdova   +2 more
doaj   +1 more source

Nonstationary Stochastic Simulation of Strong Ground-Motion Time Histories : Application to the Japanese Database [PDF]

, 2012
For earthquake-resistant design, engineering seismologists employ time-history analysis for nonlinear simulations. The nonstationary stochastic method previously developed by Pousse et al. (2006) has been updated.
Bonilla, Luis Fabian, Cotton, Fabrice, Laurendeau, Aurore   +2 more
core   +2 more sources

State-space based mass event-history model I: many decision-making agents with one target

, 2009
A dynamic decision-making system that includes a mass of indistinguishable agents could manifest impressive heterogeneity. This kind of nonhomogeneity is postulated to result from macroscopic behavioral tactics employed by almost all involved agents.
Campbell, James F., Fushing, Hsieh, Lewis, Edwin E., Shapiro-Ilan, David I., Zhu, Li   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Resonance assessment of 2-story RC framed structure using linear time history analysis methods [PDF]

MATEC Web of Conferences
In this paper, we investigate the seismic response of 2D building subjected to harmonic sinusoidal forces at the base with varying frequencies. Linear time history analysis (LTHA) is employed to evaluate the dynamic behavior of 2-story 4-bays reinforced ...
El Marzguioui Samir, El Ghoulbzouri Abdelouafi   +1 more
doaj   +1 more source

Predictability of mobile phone associations [PDF]

, 2010
Prediction and understanding of human behavior is of high importance in many modern applications and research areas ranging from context-aware services, wireless resource allocation to social sciences.
Hansen, Lars Kai, Jensen, Kristian, Larsen, Jakob Eg, Larsen, Jan, Sand Jensen, Bjørn   +4 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source