Results 91 to 100 of about 2,252,514 (265)
BuildingsEarthquakes remain one of the greatest threats to urban resilience, demanding innovative strategies that go beyond traditional earthquake-resistant design.
Betty Alvites +2 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Comparative Study of the Seismic Response of a Hotel Building With and Without Viscous Fluid Dampers
BuildingsSeismic design methods often involve high construction costs and may lead to severe structural damage during strong earthquakes. Energy dissipation technology represents an efficient approach to improving seismic performance through the integration of ...
Ariana Rodríguez +2 more
doaj +1 more source
Nigerian Journal of Technological Development, 2018 Earthquake is a natural phenomenon which is caused by sudden release of energy in the Earth's crust that creates seismic waves. Seismic response of an overhead water tank with varying foundation types subjected to five different earthquake accelerograms ...
S. O. Odeyemi +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
EngDamping modeling significantly influences the numerical seismic response of buildings, something that, despite being repeatedly emphasized in earthquake engineering research, is still overlooked even by seismic codes.
Paraskevi K. Askouni +1 more
doaj +1 more source
Time-History Analysis of Frictionally Damped Structures
, 2011 During major seismic actions, a significant amount of energy is induced to structures. The means by which this energy is dissipated, determines the level of structural degradation. Special emphasis is placed on avoiding loss of human lives due to the earthquake action.
Ştefancu, Andrei-Ionuţ +2 more
openaire +1 more source
Application of Intensifying Wind Analysis in Time History Analysis of Tall Buildings
, 2020 Abstract The wind phenomenon has always caused significant damage to structures. Suffering from extensive damage and loss over the years has led researchers to establish the novel science of wind engineering. Wind engineering references introduce wind as an intricate dynamic and random phenomenon and encourage engineers to familiarize themselves ...
openaire +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source