Results 81 to 90 of about 2,252,514 (265)

Time History Analysis in Case of a Wind Turbine

open access: yes, 2013
Due to the extended demands of the sustainability concept a new type of power source was needed at the entire world level. Therefore, in the past decade the wind turbine construction was highly extended. But this aspect came also with special design and building problems, especially in seismic areas.
Olariu, Cerasela-Panseluţa   +1 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Development of Seismic Analysis Model and Time History Analysis for KALIMER-600

open access: yesJournal of the Earthquake Engineering Society of Korea, 2007
In this paper, a simple seismic analysis model of the KALIMER-600 sodium-cooled fast reactor selected to be the candidate of the GEN-IV reactor is developed. By using this model, the seismic time history analysis is carried out to investigate the feasibilities of a seismic isolation design.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Performance-based seismic assessment of vulnerability of dam using time history analysis

open access: yesMATEC Web of Conferences, 2018
The current performance-based seismic assessment procedure can be computationally intensive as it requires many time history analyses (THA) each requiring time intensive post-processing of results.
Elmrabet Oumnia   +4 more
doaj   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Time series analysis of atmospheric-driven hydromechanical history of soft soil geo-structures [PDF]

open access: yesE3S Web of Conferences
Changing climatic conditions present an emerging threat to geo-structures. Climatic scenarios for the Netherlands indicate rising temperatures and larger variations in the atmospheric water balance.
de Wolf Inge   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Study on the Influence of Wind Load on the Safety of Magnetic Adsorption Wall-Climbing Inspection Robot for Gantry Crane

open access: yesJournal of Marine Science and Engineering
The maintenance of the surface of steel structures is crucial for ensuring the quality of shipbuilding cranes. Various types of wall-climbing robots have been proposed for inspecting diverse structures, including ships and offshore installations.
Jun Liu   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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