Results 161 to 170 of about 6,954,643 (310)

Beyond Markets and Hierarchies: Toward a New Synthesis of American Business History [PDF]

We sketch a new synthesis of American business history to replace (and subsume) that put forward by Alfred D. Chandler, Jr., most famously in his book The Visible Hand (1977).
Daniel M.G. Raff, Naomi R. Lamoreaux, Peter Temin   +2 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Prevalence and risk factors for AMS: A systematic review and meta-analysis. [PDF]

PLoS One
Liu X, Tan L, Ren Z, Bai X, Yong S, Gao H, Ba S, Gongga L.   +7 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Everyone or Just Some? Cost-Effectiveness of General Population Versus Targeted Screening Strategies for Type 1 Diabetes in Canada. [PDF]

Diabetes Care
Mital S, Schatz DA, Haller MJ, Wherrett DK, Nguyen HV.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study. [PDF]

Neurol Genet
Orr SL, Hershey AD, Kurowski BG, Langevin LM, Martin LJ, Pilipenko V, Tang K, Beauchamp MH, Craig WR, Doan Q, Zemek R, Yeates KO, as the Pediatric Emergency Research Canada A-CAP study team.   +12 more
europepmc   +1 more source

Time History Analysis in Case of a Wind Turbine

, 2013
Due to the extended demands of the sustainability concept a new type of power source was needed at the entire world level. Therefore, in the past decade the wind turbine construction was highly extended. But this aspect came also with special design and building problems, especially in seismic areas.
Olariu, Cerasela-Panseluţa, Movilă, Mihaela   +1 more
openaire   +1 more source

Statistical Software for State Space Methods [PDF]

In this paper we review the state space approach to time series analysis and establish the notation that is adopted in this special volume of the Journal of Statistical Software.
Jacques J. F. Commandeur, Marius Ooms, Siem Jan Koopman   +2 more
core   +1 more source