Results 71 to 80 of about 18,052,618 (311)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Contributions to Geophysics and Geodesy, 2019 An important, yet until now neglected, aspect of the viscoelastic behaviour of lavas is the Kramers–Kronig consistency of their complex viscoelastic shear modulus.
Martin BEDNÁRIK, Igor KOHÚT
doaj +1 more source
Sudden Stops, Time Inconsistency, and the Duration of Sovereign Debt
Social Science Research Network, 2013 We study the sovereign debt duration chosen by the government in the context of a standard model of sovereign default. The government balances off increasing the duration of its debt to mitigate rollover risk and lowering duration to mitigate the debt ...
J. Hatchondo, L. Martinez
semanticscholar +1 more source
Long-Term Contracting with Time-Inconsistent Agents [PDF]
SSRN Electronic Journal, 2018 We study contracts between naive present‐biased consumers and risk‐neutral firms. We show that the welfare loss from present bias vanishes as the contracting horizon grows. This is true both when bargaining power is on the consumers' and on the firms' side, when consumers cannot commit to long‐term contracts, and when firms do not know the consumers ...
Gottlieb, Daniel, Zhang, Xingtan
openaire +5 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A feasibility study of establishing fiscal council in Indonesia
Economic Journal of Emerging Markets, 2018 In this paper we address the quantitative measurement of credibility in fiscal policy in the case of Indonesia over the period 2001-2016. This preliminary paper focuses on the deviations of the actual budget balances from the projections about these ...
Haryo Kuncoro
doaj +3 more sources
Time Inconsistency and Free-Riding in a Monetary Union [PDF]
We analyze the setting of monetary and nonmonetary policies in monetary unions. We show that in these unions a time inconsistency problem in monetary policy leads to a novel type of free-rider problem in the setting of nonmonetary policies, such as labor
Patrick J. Kehoe, V. V. Chari
core +3 more sources
Reliability and Availability Models of Belt Drive Systems Considering Failure Dependence
Chinese Journal of Mechanical Engineering, 2019 Conventional reliability models of belt drive systems in the failure mode of fatigue are mainly based on the static stress strength interference model and its extended models, which cannot consider dynamic factors in the operational duration and be used ...
Peng Gao, Liyang Xie, Jun Pan
doaj +1 more source