Results 181 to 190 of about 36,815 (253)

AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network. [PDF]

Nat Methods
Fadini A, Li M, McCoy AJ, Banjara S, Okumura H, Napier E, Fontana P, Khan AR, Jovine L, Terwilliger TC, Read RJ, Hekstra DR, AlQuraishi M.   +12 more
europepmc   +1 more source

Spotlight on the Nucleotide: Solid‐State NMR for the Investigation of ATP Hydrolysis in the ATPase SmsC

Chemistry – A European Journal, EarlyView.
Nucleotide‐detected solid‐state NMR has been applied to probe nucleotide conformations and dynamics during ATP hydrolysis using the dimeric P‐loop ATPase SmsC as a model protein. The different stages of ATP hydrolysis have been mimicked by ATP analogues for which different degrees of conformational heterogeneity have been observed. ABSTRACT Solid‐state
Nina Wehr, Laure Decamps, Julius Schlüter, Koen Linssen, Georg Künze, Kushal Sengupta, Serena DeBeer, Thomas Wiegand   +7 more
wiley   +1 more source

Synthesis and Optical Properties of Diboron Complexes of 1,4‐Anthraquinone Derivatives

Chemistry – A European Journal, EarlyView.
1,4‐Diboron complexes exhibit near‐infrared fluorescence, in contrast to non‐emissive 1,5‐diboron analogues. Fluorescence quantum yields decrease with increasing electron‐donating substituents, attributed to enhanced nonradiative decay via intramolecular PeT.
Yasuhiro Kubota, Ayumi Ogasawara, Ayato Hakamada, Naoya Suzuki, Masayasu Taki, Shota Mizuno, Toshiyasu Inuzuka, Kazumasa Funabiki, Chie Yamada‐Kubota, Miho Kuwahara, Tetsuya Hara   +10 more
wiley   +1 more source

Compact tape-driven sample delivery system for serial femtosecond crystallography. [PDF]

J Appl Crystallogr
Kang J, Shimazu Y, Luo F, Yamashita A, Tanaka T, Inubushi Y, Tono K, Nuemket N, Orville AM, Iwata S, Nango E, Yabashi M.   +11 more
europepmc   +1 more source

Routes to Cyclobutadiene and Cycloallyl Pt(II) Complexes: Dicationic Bis(Alkyne) Species as Intermediates

Chemistry – A European Journal, EarlyView.
This work demonstrates the synthesis of cationic Pt(II) η3‐cycloallyl complexes, and experimental and computational studies show a ligand bite‐angle dependence of their formation rates. The reactivity of these complexes with Brønsted acids was investigated, leading to the formation of cationic and dicationic Pt(II) η4‐cyclobutadiene complexes ...
Ouchan He, Froze Jameel, Y. Einar H. Stampehl, Liza M. Richter, Matteo Tosi, Martin Kaupp, Thomas Braun   +6 more
wiley   +1 more source

Plant structural biology: Emerging technologies and future biological insights. [PDF]

Plant J
Böhm JM, Maurino VG.
europepmc   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

Chemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal, Alexandre Millanvois, Louis Fensterbank, Cyril Ollivier   +3 more
wiley   +1 more source

Structural pharmacology of Chinese medicine: technological breakthroughs in decoding multi-target synergy and precision mechanisms. [PDF]

Adv Biotechnol (Singap)
Wang C, Li Y, Zhuo L, Xu S, Wang M, Liu Z.   +5 more
europepmc   +1 more source

Stereoretentive Nucleophilic Aromatic Substitution Accesses Atropisomeric 4‐Amino‐N‐Arylquinolinium Salts

Chemistry – A European Journal, EarlyView.
Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes, Nia Foster, Saima Ansari, Paul Kavanagh, Paul Dingwall, Peter C. Knipe   +5 more
wiley   +1 more source

A user-friendly goniometer-compatible fixed-target platform for macromolecular crystallography at synchrotrons. [PDF]

J Appl Crystallogr
Ghosh S, Banacore A, Norder P, Bjelčić M, Kabbinale A, Nileshwar P, Wehlander G, de Sanctis D, Basu S, Orlans J, Vallejos A, Chavas LMG, Neutze R, Brändén G.   +13 more
europepmc   +1 more source