Results 161 to 170 of about 9,379,767 (301)
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Time-resolved studies of ultrafast wavepacket dynamics in hydrogen molecules
C. R. Calvert +3 more
semanticscholar +1 more source
Dataset of audiovisual unscripted monologues with speech annotations. [PDF]
Jaeger M +3 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Time-Resolved Native Mass Spectrometry for Direct Measurement of Biomolecular Kinetics. [PDF]
James VK +10 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Time-resolved studies of the photodissociation of adenine [PDF]
A novel time-resolved velocity map ion imaging (TR-VMI) experiment has been\ud constructed and successfully applied to the study of non-statistical dissociation\ud processes.\ud The photodissociation of NH3 following the population of the ν2\ud ’ = 4 umbrella\ud vibrational mode of the first electronically excited, Ã1A2”, singlet state, was\ud ...
openaire
Editorial: Navigating the microbial landscape: integrating mass spectrometry imaging and other multimodal imaging approaches for spatially resolved microbial studies. [PDF]
Tuck MD, Feucherolles M, Verhaert PDEM.
europepmc +1 more source

