Results 211 to 220 of about 132,546 (251)

Time-restricted feeding and circadian autophagy for long life

Nature Reviews Endocrinology, 2021
Time-restricted feeding (TRF) has shown many health benefits in different organisms, but its effect on lifespan is unknown. A new study showed that a novel intermittent TRF (iTRF) dietary regimen can extend the healthy lifespan of Drosophila. A clock-dependent nightly rise in autophagy drives the lifespan benefits of iTRF.
Hong Long, Satchidananda Panda
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Circadian regulation of appetite and time restricted feeding

Physiology & Behavior, 2020
The circadian system plays an important role in the temporal regulation of metabolic processes as well as food intake to ensure energy efficiency. The 'master' clock is located within the superchiasmatic nucleus and receives input from the retina so that it can be entrained by the light:dark cycle. In turn, the master clock entrains other clocks in the
Amanda J, Page, Stewart, Christie, Erin, Symonds, Hui, Li   +3 more
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Circadian misalignment in obesity: The role for time-restricted feeding

Clinical Nutrition ESPEN, 2023
The epidemic of obesity is associated with a substantial, complex and escalating burden of disease. Dietary and lifestyle interventions provide the mainstay of management; however, obesity is multifactorial and challenging to address clinically. Disrupted circadian behaviours, including late eating, are associated with obesity. Time-restricted feeding (
Lydia Chambers, Karin Seidler, Michelle Barrow   +2 more
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Time-restricted Feeding Changes as Inspiration for Drug Design

Current Pharmaceutical Design, 2023
: Time-restricted feeding (TRF) is a special lifestyle intervention that improves glucose metabolism, regulates lipid metabolism, increases gut micro richness, and strengthens circadian rhythm. Diabetes is a remarkable component of metabolic syndrome, and individuals with diabetes can benefit from TRF.
Zhangyuting, He, Huayu, Yang, Yilei, Mao
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Finding balance: understanding the energetics of time‐restricted feeding in mice

Obesity, 2022
AbstractOver the course of mammalian evolution, the ability to store energy likely conferred a survival advantage when food became scarce. A long‐term increase in energy storage results from an imbalance between energy intake and energy expenditure, two tightly regulated parameters that generally balance out to maintain a fairly stable body weight ...
Molly R. Gallop, Selene Y. Tobin, Amandine Chaix   +2 more
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A muscle-centric view of time-restricted feeding for older adults

Current Opinion in Clinical Nutrition & Metabolic Care, 2021
Purpose of review The practice of time-restricted feeding (TRF) has received fervent interest in recent years as a strategy to mitigate obesity and metabolic disease. We sought to review the implications of TRF for skeletal muscle health and function in aging.
Matthew J, Lees, Nathan, Hodson, Daniel R, Moore   +2 more
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Time-restricted feeding mitigates obesity through adipocyte thermogenesis

Science, 2022
Misalignment of feeding rhythms with the light-dark cycle leads to disrupted peripheral circadian clocks and obesity. Conversely, restricting feeding to the active period mitigates metabolic syndrome through mechanisms that remain unknown. We found that genetic enhancement of adipocyte thermogenesis through ablation of the zinc finger protein 423 ...
Chelsea Hepler, Benjamin J. Weidemann, Nathan J. Waldeck, Biliana Marcheva, Jonathan Cedernaes, Anneke K. Thorne, Yumiko Kobayashi, Rino Nozawa, Marsha V. Newman, Peng Gao, Mengle Shao, Kathryn M. Ramsey, Rana K. Gupta, Joseph Bass   +13 more
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Time-restricted feeding alters the efficiency of mammary tumor growth

Chronobiology International, 2021
Disruption of circadian rhythms has detrimental host consequences. Indeed, both clinical and foundational science demonstrate a clear relationship between disruption of circadian rhythms and cancer initiation and progression. Because timing of food intake can act as a zeitgeber (i.e., entrainment signal) for the circadian clock, and most individuals in
William H. Walker, Alexis L. Kaper, O. Hecmarie Meléndez-Fernández, Jacob R. Bumgarner, Jennifer A. Liu, James C. Walton, A. Courtney DeVries, Randy J. Nelson   +7 more
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Time-Restricted Feeding (16/8)

Topics in Clinical Nutrition
This study aimed to investigate the effects of 8-hour time-restricted feeding (TRF) on body weight, biochemical parameters, diet quality, and eating behavior in overweight females. In the TRF group, there was a statistically significant decrease in body weight, body mass index, and waist and hip circumference (P < .05).
Ayşen Yıldırım Kızıldağ, Sema Erge, Umut Haklıgil   +2 more
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Abstract 13582: The Effect of Time-restricted Feeding on Weight: A Randomized Feeding Trial

Circulation, 2020
Introduction: Time-restricted feeding (TRF) may improve cardiometabolic outcomes. Prior studies of TRF in humans were limited by lack of randomization and controlled feeding, inadequate sample size and short duration. Hypothesis: Participants following a TRF pattern will lose more ...
Nisa Maruthur, Scott Pilla, May T Maw, Daisy Duan, Di Zhao, Eliseo Guallar, Ruth Alma Turkson Ocran, Karen White, Beiwen Wu, Jeanne Charleston, Lawrence J Appel, Jeanne M Clark   +11 more
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