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Time-restricted Feeding Changes as Inspiration for Drug Design

Current Pharmaceutical Design, 2023
: Time-restricted feeding (TRF) is a special lifestyle intervention that improves glucose metabolism, regulates lipid metabolism, increases gut micro richness, and strengthens circadian rhythm. Diabetes is a remarkable component of metabolic syndrome, and individuals with diabetes can benefit from TRF.
Zhangyuting, He, Huayu, Yang, Yilei, Mao
openaire   +2 more sources

Finding balance: understanding the energetics of time‐restricted feeding in mice

Obesity, 2022
AbstractOver the course of mammalian evolution, the ability to store energy likely conferred a survival advantage when food became scarce. A long‐term increase in energy storage results from an imbalance between energy intake and energy expenditure, two tightly regulated parameters that generally balance out to maintain a fairly stable body weight ...
Molly R. Gallop   +2 more
openaire   +2 more sources

A muscle-centric view of time-restricted feeding for older adults

Current Opinion in Clinical Nutrition & Metabolic Care, 2021
Purpose of review The practice of time-restricted feeding (TRF) has received fervent interest in recent years as a strategy to mitigate obesity and metabolic disease. We sought to review the implications of TRF for skeletal muscle health and function in aging.
Matthew J, Lees   +2 more
openaire   +2 more sources

Time-restricted feeding alters the efficiency of mammary tumor growth

Chronobiology International, 2021
Disruption of circadian rhythms has detrimental host consequences. Indeed, both clinical and foundational science demonstrate a clear relationship between disruption of circadian rhythms and cancer initiation and progression. Because timing of food intake can act as a zeitgeber (i.e., entrainment signal) for the circadian clock, and most individuals in
William H. Walker   +7 more
openaire   +2 more sources

Effects of time-restricted feeding (16/8) combined with a low-sugar diet on the management of non-alcoholic fatty liver disease: A randomized controlled trial.

Nutrition (Burbank, Los Angeles County, Calif.), 2022
OBJECTIVES Emerging studies have employed time-restricted feeding (TRF) and a low-sugar diet alone in the management of non-alcoholic fatty liver disease (NAFLD), but their combination has not been tested.
H. Kord-Varkaneh   +4 more
semanticscholar   +1 more source

Role of the Circadian Clock and Effect of Time-Restricted Feeding in Adenine-Induced Chronic Kidney Disease.

Laboratory investigation; a journal of technical methods and pathology, 2023
Most physiological functions exhibit circadian rhythmicity that is partly regulated by the molecular circadian clock. Herein, we investigated the relationship between the circadian clock and chronic kidney disease (CKD).
Yi-Na Fang   +10 more
semanticscholar   +1 more source

Time‐Restricted Feeding Improves Glucose Tolerance in Men at Risk for Type 2 Diabetes: A Randomized Crossover Trial

Obesity, 2019
This study aimed to assess the effects of 9‐hour time‐restricted feeding (TRF), early (TRFe) or delayed (TRFd), on glucose tolerance in men at risk for type 2 diabetes.
Amy T. Hutchison   +6 more
semanticscholar   +1 more source

Abstract 13582: The Effect of Time-restricted Feeding on Weight: A Randomized Feeding Trial

Circulation, 2020
Introduction: Time-restricted feeding (TRF) may improve cardiometabolic outcomes. Prior studies of TRF in humans were limited by lack of randomization and controlled feeding, inadequate sample size and short duration. Hypothesis: Participants following a TRF pattern will lose more ...
Nisa Maruthur   +11 more
openaire   +1 more source

Unraveling the Health Benefits and Mechanisms of Time-Restricted Feeding: Beyond Caloric Restriction.

Nutrition reviews
Time-restricted feeding (TRF) is a lifestyle intervention that aims to maintain a consistent daily cycle of feeding and fasting to support robust circadian rhythms. Recently, it has gained scientific, medical, and public attention due to its potential to
Ru-Han Wang   +3 more
semanticscholar   +1 more source

Different time-restricted feeding patterns potentially modulate metabolic health by altering tryptophan metabolism of gut microbes in pigs.

Food Research International
Time-restricted feeding has emerged as a preferred approach for alleviating metabolic disorders, but the potential microbiological mechanism remains poorly understood. This study used a growing pig model to mimic common-sense eating habits.
Qiuke Li   +7 more
semanticscholar   +1 more source

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