Results 101 to 110 of about 13,606,645 (327)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Multiple Time Series Analysis [PDF]
, 2000 This chapter demonstrates how to use XploRe for specifying, estimating, and interpreting vector autoregressive (VAR) models. VAR modeling belongs to multiple time series analysis. It is one approach in econometrics to describe a system of more than one equation and was introduced by Sims (1980). The classical multi equation modeling (e.g. Dhrymes, 1978)
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
We provide a concise overview of time series analysis in the time and frequency domains, with lots of references for further reading.time series analysis, time domain, frequency ...
Francis X. Diebold +2 more
core +2 more sources
Time averaging, ageing and delay analysis of financial time series
New Journal of Physics, 2017 We introduce three strategies for the analysis of financial time series based on time averaged observables. These comprise the time averaged mean squared displacement (MSD) as well as the ageing and delay time methods for varying fractions of the ...
Andrey G Cherstvy +4 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Univariant time series analysis applied to ozone forecasting in the city of Cali, Colombia
Revista Facultad de Ingeniería Universidad de Antioquia, 2014 The modelling results of tropospheric ozone concentration in the urban area of Cali, Colombia, suitable for short term forecasting, are presented. Results were obtained by using an univariate time series analysis.
Mauricio Jaramillo Ayerbe +4 more
doaj +1 more source
Symbolic Time Series Analysis in Economics [PDF]
In this paper I describe and apply the methods of Symbolic Time Series Analysis (STSA) to an experimental framework. The idea behind Symbolic Time Series Analysis is simple: the values of a given time series data are transformed into a finite set of ...
Juan Gabriel Brida
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source