Results 41 to 50 of about 7,950,405 (275)

Variability of Air Temperature, Precipitation and Outflows in the Vistula Basin (Poland)

Resources, 2020
This study examines trends in temperature, precipitation and discharge rates over a 65-year observation period (1951–2015) and compares the two sub-periods 1951–1980 and 1981–2015. The research was carried out on annual and monthly values.
Katarzyna Kubiak-Wójcicka
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Scaling analysis of multivariate intermittent time series

, 2005
The scaling properties of the time series of asset prices and trading volumes of stock markets are analysed. It is shown that similarly to the asset prices, the trading volume data obey multi-scaling length-distribution of low-variability periods. In the
Ausloos, Bachmann, Benzi, Bernaola-Galván, Black, Fama, Fama, Fama, Fujiwara, Fujiwara, Gabaix, Gabaix, Gopikrishnan, Jaan Kalda, Kitt, Mandelbrot, Mandelbrot, Mantegna, Mantegna, Markowitz, Maslov, Murphy, Robert Kitt, Sharpe, Shlesinger, Säkki, Vandewalle, Voit, Zipf   +28 more
core   +2 more sources

Multiple Time Series Analysis [PDF]

, 2000
This chapter demonstrates how to use XploRe for specifying, estimating, and interpreting vector autoregressive (VAR) models. VAR modeling belongs to multiple time series analysis. It is one approach in econometrics to describe a system of more than one equation and was introduced by Sims (1980). The classical multi equation modeling (e.g. Dhrymes, 1978)
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Multifractal detrended fluctuation analysis of nonstationary time series [PDF]

, 2002
We develop a method for the multifractal characterization of nonstationary time series, which is based on a generalization of the detrended fluctuation analysis (DFA).
Alados, Amaral, Armin Bunde, Arneodo, Arneodo, Arneodo, Arneodo, Arneodo, Ashkenazy, Ashkenazy, Bacry, Bahar, Barabási, Blesic, Buldyrev, Buldyrev, Bunde, Chen, Eva Koscielny-Bunde, Feder, H.Eugene Stanley, Hausdorff, Hu, Ivanov, Ivanov, Ivanova, Ivanova, Jaffard, Jan W. Kantelhardt, Kantelhardt, Kantelhardt, Koscielny-Bunde, Liu, Makse, Malamud, Mantegna, Muzy, Muzy, Nakao, Ossadnik, Peitgen, Peng, Peng, Shlesinger, Shlomo Havlin, Silchenko, Stephan A. Zschiegner, Talkner, Taqqu, Vandewalle, Vandewalle   +50 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Cyclic Nonlinear Correlation Analysis for Time Series

IEEE Access, 2022
Principal component analysis (PCA) and kernel PCA allow the decorrelation of data with respect to a basis that is found via variance maximization. However, these techniques are based on pointwise correlations.
Christopher M. A. Bonenberger, Friedhelm Schwenker, Wolfgang Ertel, Markus Schneider   +3 more
doaj   +1 more source