Results 81 to 90 of about 7,950,405 (275)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Complexity Analysis of Environmental Time Series

Entropy
Small, forested catchments are prototypes of terrestrial ecosystems and have been studied in several disciplines of environmental science over several decades.
Holger Lange, Michael Hauhs
doaj   +1 more source

Bayesian time series analysis of terrestrial impact cratering

, 2011
Giant impacts by comets and asteroids have probably had an important influence on terrestrial biological evolution. We know of around 180 high velocity impact craters on the Earth with ages up to 2400Myr and diameters up to 300km.
Alvarez, Alvarez, Alvarez, Bahcall, Bailer-Jones, Berger, Berger, Broadbent, C. A. L. Bailer-Jones, Chang, Christensen, Davis, Deutsch, Gardner, Gregory, Grieve, Grieve, Grieve, Grieve, Hallam, Heisler, Jaynes, Jeffreys, Jetsu, Kass, Le Feuvre, Lyytinen, Mackay, Marden, Matsumoto, McEwen, Montanari, Napier, Napier, Rampino, Shoemaker, Shuter, Stigler, Stigler, Stothers, Torbett, Wickramasinghe, Yabushita, Yabushita, Yabushita   +44 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MULTIVARIATE ANALYSIS IN VECTOR TIME SERIES [PDF]

This paper reviews the applications of classical multivariate techniques for discrimination, clustering and dimension reduction for time series data. It is shown that the discrimination problem can be seen as a model selection problem.
Daniel Peña, Pedro Galeano
core  

Detection of time reversibility in time series by ordinal patterns analysis

, 2018
Time irreversibility is a common signature of nonlinear processes, and a fundamental property of non-equilibrium systems driven by non-conservative forces.
Chavez, Mario, Herrera-Diestra, José L., Martínez, Johann H.   +2 more
core   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Time averaging, ageing and delay analysis of financial time series

New Journal of Physics, 2017
We introduce three strategies for the analysis of financial time series based on time averaged observables. These comprise the time averaged mean squared displacement (MSD) as well as the ageing and delay time methods for varying fractions of the ...
Andrey G Cherstvy, Deepak Vinod, Erez Aghion, Aleksei V Chechkin, Ralf Metzler   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Univariant time series analysis applied to ozone forecasting in the city of Cali, Colombia

Revista Facultad de Ingeniería Universidad de Antioquia, 2014
The modelling results of tropospheric ozone concentration in the urban area of Cali, Colombia, suitable for short term forecasting, are presented. Results were obtained by using an univariate time series analysis.
Mauricio Jaramillo Ayerbe, Daniel Enrique González Gómez, María Eugenia Núñez Cabrera, Gloria Esperanza Portilla, Jesús Heriberto Lucio García   +4 more
doaj   +1 more source