Results 111 to 120 of about 89,230,702 (250)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Bringing requirements engineering to formal methods: timing diagrams for Event-B and KAOS

, 2010
Event-B is a language for the formal development of reactive systems. At present the RODIN toolkit (RODIN, 2009) for Event-B is used for modelling requirements, specifying refinements and verification.
Joochim, Tossaporn
core   +1 more source

Information fraction estimation: Strategies for a phase 3 non-inferiority maximum duration design with time to event outcome. [PDF]

Pharm Stat, 2023
Dang HM, Krailo MD, Alonzo TA, Mack WJ, Kairalla JA.   +4 more
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Preliminary evidence for chaotic signatures in host-microbe interactions

mSystems
Host-microbe interactions constitute dynamical systems that can be represented by mathematical formulations that determine their dynamic nature and are categorized as deterministic, stochastic, or chaotic.
Yehonatan Sella, Nichole A. Broderick, Kaitlin M. Stouffer, Deborah L. McEwan, Frederick M. Ausubel, Arturo Casadevall, Aviv Bergman   +6 more
doaj   +1 more source

Calculating the power of a planned individual participant data meta-analysis of randomised trials to examine a treatment-covariate interaction with a time-to-event outcome. [PDF]

Res Synth Methods, 2023
Riley RD, Collins GS, Hattle M, Whittle R, Ensor J.   +4 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Supplemental material for A latent class approach for joint modeling of a time-to-event outcome and multiple longitudinal biomarkers subject to limits of detection

, 2019
Supplemental Material for A latent class approach for joint modeling of a time-to-event outcome and multiple longitudinal biomarkers subject to limits of detection by Menghan Li, Ching-Wen Lee and Lan Kong in Statistical Methods in Medical ...
Lan Kong (347791), Ching-Wen Lee (7332446), Menghan Li (7332443)   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Risk Projection for Time-to-event Outcome Leveraging Summary Statistics With Source Individual-level Data. [PDF]

J Am Stat Assoc, 2022
Zheng J, Zheng Y, Hsu L.
europepmc   +1 more source