Risk projection for time-to-event outcome from population-based case-control studies leveraging summary statistics from the target population. [PDF]
Lifetime Data AnalZheng J, Hsu L.
europepmc +1 more source
A new method for analysing transition to psychosis: Joint modelling of time-to-event outcome with time-dependent predictors. [PDF]
Int J Methods Psychiatr Res, 2018 Yuen HP, Mackinnon A, Nelson B.
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
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A combined test for a generalized treatment effect in clinical trials with a time-to-event outcome. [PDF]
Stata J, 2017 Royston P.
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
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Joint Models for Multiple Longitudinal Processes and Time-to-event Outcome. [PDF]
J Stat Comput Simul, 2016 Yang L, Yu M, Gao S.
europepmc +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
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A Bayesian approach for instrumental variable analysis with censored time-to-event outcome. [PDF]
Stat Med, 2015 Li G, Lu X.
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
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