Results 91 to 100 of about 64,685,758 (285)

Clinical Features and Time to Recovery of Admitted COVID-19 Cases at Dilla University Referral Hospital Treatment Center, South Ethiopia

Infection and Drug Resistance, 2022
Gemechu Churiso,1 Kuma Diriba,1 Henok Girma,2 Soressa Tafere3 1Department of Medical Laboratory Sciences, Dilla University, Dilla, Ethiopia; 2Ohio State University, Global One Health Initiative, Dilla, Ethiopia; 3COVID-19 Treatment Center, Dilla ...
Churiso G, Diriba K, Girma H, Tafere S
doaj  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Duration of recovery from severe acute malnutrition and associated factors in children aged 6–59 months: a retrospective cohort study

Scientific Reports
Malnutrition, particularly severe acute malnutrition (SAM) in children under five, is a global crisis affecting 25–35 million children, especially in Africa and Southeast Asia. In Ethiopia, 21% are underweight, 36% stunted, and 7% wasted.
Hikma Fedlu, Lata Fekadu, Amanuel Mengistu Merera, Kumara Asafa, Firew Tiruneh   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Return to sports and physical activity after implantable shock absorber surgery for patients with medial knee osteoarthritis

Journal of Cartilage & Joint Preservation
: Objectives: Symptomatic knee osteoarthritis (OA) is a leading cause of disability. High tibial osteotomy and knee arthroplasty can deliver excellent outcomes, but are complicated by morbidity, times, and activity limitation.
Seth L. Sherman, Anil S. Ranawat, Marcin Domzalski, Dennis C. Crawford   +3 more
doaj   +1 more source

Effects of kinesiology taping timing on recovery in the lower limbs

Frontiers in Physiology
BackgroundKinesiology taping (KT) is widely used to support muscle function and recovery, but its optimal application timing remains unclear. While some suggest pre-exercise KT provides protective benefits, others propose post-exercise KT aids recovery.
Chia-Yu Tang, Ying-Che Huang, Ying-Che Huang, Fu-Shun Hsu, Fu-Shun Hsu, Fu-Shun Hsu, Chia-Hsien Yu, Chang-Chi Lai, Szu-Kai Fu   +8 more
openaire   +3 more sources

Industrial HVAC Air-to-Air Energy Recovery Retrofit Economics

, 1980
Retrofitting air-to-air energy recovery equipment is relatively simply to design and easy to install. Additionally, HVAC energy recovery is almost risk free when compared to process retrofit.
Graham, E. L.
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source