Results 111 to 120 of about 1,223,971 (333)

Liquidity, time‐varying betas and anomalies: Is the high trading activity enhancing the validity of the CAPM in the UK equity market?

, 2020
Javier Rojo‐Suárez, Ana Belén Alonso‐Conde, Ricardo Ferrero Pozo   +2 more
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Building a Beta‐Lactam Model‐Informed Precision Dosing Service in a Quaternary Care Children's Hospital

Clinical and Translational Science
There has been growing interest in precision dosing of beta‐lactam antibiotics in recent years. At our institution, a quaternary children's hospital, we launched a new PK consult service utilizing a model‐informed precision dosing (MIPD) approach to ...
Sonya Tang Girdwood, Ronaldo Morales Junior, Erin Schuler, Peter Tang, Emily Diseroad, Catherine Misch, Beverly Engle, Shawn McCall, Mark E. Murphy, Zachary L. Taylor, Tomoyuki Mizuno, Alexander A. Vinks, Jennifer Kaplan   +12 more
doaj   +1 more source

Estimating Time-Varying Currency Betas: New Evidence from Nine Developed and Emerging Markets

, 2013
Ling Long, Albert K. Tsui, Zhaoyong Zhang   +2 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Time-Varying Beta and the Value Premium: A Single-Index Varying-Coefficient Model Approach

, 2015
Hui Guo, Chaojiang Wu, Yan Yu
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Optimization and clinical validation of a Real-Time PCR protocol for direct detection of Trichomonas vaginalis in pooled urine samples

Iranian Journal of Microbiology, 2009
Background and Objectives: A new Real- Time PCR protocol for the detection of Trichomonas vaginalis in pooled urine samples has been optimized and validated.
WB van Leeuwen, WHA Zandijk
doaj  

Optical solutions to the time fractional Akbota equation arising in nonlinear optics via two distinct methods

Scientific Reports
This paper investigates the optical soliton solutions of the time-fractional Akbota equation, a model arising in nonlinear optics. The generalized rational function method and the F-expansion approach are utilized to derive soliton solutions ...
Salim S. Mahmood, Salah Mahmoud Boulaaras, Muhammad Amin S. Murad, Sandeep Malik   +3 more
doaj   +1 more source

A Model for Estimating Time Varying Sector Betas: A State Space Approach

, 2009
Nicolai Schipper Jespersen
openalex   +1 more source