Results 101 to 110 of about 1,533,087 (281)
2014 IEEE Conference on Computer Vision and Pattern Recognition, 2014 We explore whether we can observe Time's Arrow in a temporal sequence -- is it possible to tell whether a video is running forwards or backwards? We investigate this somewhat philosophical question using computer vision and machine learning techniques. We explore three methods by which we might detect Time's Arrow in video sequences, based on distinct ...
Pickup, LC +7 more
openaire +2 more sources
Gravitational Entropy and Inflation
Entropy, 2013 The main topic of this paper is a description of the generation of entropy at the end of the inflationary era. As a generalization of the present standard model of the Universe dominated by pressureless dust and a Lorentz invariant vacuum energy (LIVE ...
Øystein Elgarøy, Øyvind Grøn
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Arrow of Time: Challenges for Sociological Knowledge
Социологическая наука и социальная практика, 2014 The author analyzes new challenges appeared as a result of the becoming of the complex socium. It is shown that these vulnerabilities manifest new risks for the functioning of the society and its members.
Sergey A. Kravchenko
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2011 It’s an anniversary of sorts. Not today, nor any particular day this year, but this year, 2011, marks my 15th year doing research. The last time I blogged about this was the 10th anniversary, back in 2006. Back then I was in my fifth year as a PhD student in Kevin Padian’s lab at Berkeley.
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On the time arrows, and randomness in cosmological signals
EPJ Web of Conferences, 2013 Arrows of time - thermodynamical, cosmological, electromagnetic, quantum mechanical, psychological - are basic properties of Nature. For a quantum system-bath closed system the de-correlated initial conditions and no-memory (Markovian) dynamics are ...
Gurzadyan V.G., Sargsyan S., Yegorian G.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source