Results 121 to 130 of about 731,597 (291)
Natural Science What does the " arrow of time " stand for?
, 2010 International audienceOne hundred and thirty years after the work of Ludwig Boltzmann on the interpretation of the irreversibility of physical phenomena, and one century after Einstein's formulation of Special Relativity, we are still not sure what we ...
Klein, Etienne
core +1 more source
Emergence of opposing arrows of time in open quantum systems
Scientific ReportsDeriving an arrow of time from time-reversal symmetric microscopic dynamics is a fundamental open problem in many areas of physics, ranging from cosmology, to particle physics, to thermodynamics and statistical mechanics.
Thomas Guff +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Arrow of time in dissipationless cosmology
, 2020 © 2015 IOP Publishing Ltd. It is generally believed that a cosmological arrow of time must be associated with entropy production. Indeed, in his seminal work on cyclic cosmology, Tolman introduced a viscous fluid in order to make successive expansion ...
Sahni V., Shtanov Y., Toporensky A.
core
, 1978 Caltech's 1978 commencement speaker muses on the direction in which the Institute intended--and ought--to continue its greatest ...
Delbruck, Max
core
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Origins of Time-asymmetry in Thermodynamics: The Minus First Law [PDF]
, 2001 This paper investigates what the source of time-asymmetry is in thermodynamics, and comments on the question whether a time-symmetric formulation of the Second Law is ...
Uffink, Jos +3 more
core
Future TransportationVirtual reality driving simulators have been increasingly used for training purposes, but they are still lacking effective driver assistance features, and poor use of user interface (UI) and guidance systems leads to users’ performance being affected. In
Numan Ali +4 more
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source