Results 131 to 140 of about 12,731,770 (288)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Time's Arrow, February 11, 2013 [PDF]
, 2013 This is the concert program of the Time's Arrow performance on Monday, February 11, 2013 at 8:00 p.m., at The Art Gallery, 808 Commonwealth Avenue, Boston, Massachusetts. Works performed were Form No. 3 by James Tenney, Form No.
School of Music, Boston University
core +1 more source
Future TransportationVirtual reality driving simulators have been increasingly used for training purposes, but they are still lacking effective driver assistance features, and poor use of user interface (UI) and guidance systems leads to users’ performance being affected. In
Numan Ali +4 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Repositories: What\u27s the target? An ARROW Perspective [PDF]
, 2005 The key observation about institutional research repositories is that they are under-used. This paper looks at why take-up has been slow, and what might encourage researchers to use these facilities.
Whitehead, Derek
core
Time arrow without past hypothesis: a toy model explanation
New Journal of PhysicsThe laws of Physics are time-reversible, making no qualitative distinction between the past and the future—yet we can only go towards the future. This apparent contradiction is known as the ‘arrow of time problem’.
Pablo Arrighi +2 more
doaj +1 more source
Time arrow in published clinical studies/trials indexed in MEDLINE: a systematic analysis of retrospective vs. prospective study design, from 1960 to 2017. [PDF]
PeerJ, 2019 Ciulla MM, Vivona P.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 1972 Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
core