Results 111 to 120 of about 2,455,455 (282)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Applying population‐specific incidence prevalence ratio benchmarks to monitor the Australian HIV epidemic: an epidemiological analysis

Journal of the International AIDS Society
Introduction Due to a lack of robust population denominators, Australia is unable to accurately monitor changes in the HIV epidemic for some populations.
Jonathan M. King, Hamish McManus, Richard T. Gray, Steven J. Nigro, Jana Sisnowski, Timothy Dobbins, Benjamin R. Bavinton, Andrew E. Grulich, Kathy Petoumenos, Jane Costello, Skye McGregor   +10 more
doaj   +1 more source

Mr imaging of the knee at 3t – diagnostic performance and comparison with 1.5t

Journal of the Belgian Society of Radiology, 2014
The range of available magnetic field strengths for clinical knee MRI has expanded over the last 20 years, from below 0.2T to 1.5T, and, recently, 7T.
P Van Dyck
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Light-emitting diodes and photodiodes in the deep ultra-violet range for absorption photometry in liquid chromatography, capillary electrophoresis and gas sensing [PDF]

, 2016
Absorbance measurement in the deep ultra-violet range (below 300 nm) has been one of the most widely used detection methods for analytical techniques as a large number of organic compounds have strong absorption bands in the deep UV region.
Bui, Duy Anh
core   +1 more source

Improved Glycemic Control during a One-Week Adventure Camp in Adolescents with Type 1 Diabetes—The DIACAMP Study

Biosensors
Adolescence remains a crucial age associated with diabetes distress in individuals living with type 1 diabetes (T1D). The Austrian organization “Diabär” regularly hosts a one-week adventure camp for adolescents (12–18 years) living with T1D.
Antonia-Therese Kietaibl, Faisal Aziz, Eva Wurm, Celine Tomka, Elke Fröhlich-Reiterer, Othmar Moser, Thomas R. Pieber, Peter Fasching, Julia K. Mader, Harald Sourij, Felix Aberer   +10 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Protein supplementation and 48-hour calf removal effects on range cows

, 1992
In 1984, 99 Angus X Hereford cows (4- to 6-yr-olds) were assigned randomly to a 4-yr, 2 X 2 factorial study. Treatment assignment was permanent, and no new cows were added during the study.
Wallace, J. D., Sowell, B. F., Parker, E. E., Southward, G. M.   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Phosphorus supplementation of range cows in the Northern Great Plains

, 1997
Low phosphorus (P) levels in Northern Great Plains rangeland forage combined with limited data on the P requirements of range cows (Bos taurus), precipitated 2 studies conducted to compare the performance of P supplemented and no P supplemented (control)
Karn, J. F.
core   +1 more source