Results 181 to 190 of about 1,536,819 (313)

Statistical framework for video decoding complexity modeling and prediction

, 2009
Video decoding complexity modeling and prediction is an increasingly important issue for efficient resource utilization in a variety of applications, including task scheduling, receiver-driven complexity shaping, and adaptive dynamic voltage scaling.
Andreopoulos, Y, Kontorinis, N, Van Der Schaar, M   +2 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Complexity and communities: The application of complexity to community studies

, 2015
Understanding community dynamics has always been a challenge for policy-makers. Often community policy has been ineffective and wasteful. This research explores and sets out an alternative, complexity-informed approach to community studies.
Large, David
core  

Speed and quality of complex strategic decisions. [PDF]

Proc Natl Acad Sci U S A
Sunde U, Zegners D, Strittmatter A.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Dynamic Electrocortical States and Paradoxical Complexity during Desflurane Anesthesia. [PDF]

Anesthesiology
Li D, Hudetz AG.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Enhancing Physiological Complexity Through Mindfulness: A Wearable-Based Intervention for First Responders and Their Partners. [PDF]

Healthcare (Basel)
Lockhart TE, Soangra R, Frames C, Lee SK, Martin A, Lee S, Gewirtz AH.   +6 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A Reduced-Complexity Partial-Interference-Cancellation Group Decoder for STBCs

In this paper, we propose a reduced-complexity implementation of partial interference cancellation group decoder with successive interference cancellation (PIC-GD-SIC) by employing the theory of displacement structures.
Hari, K. V. S., Rajashekar, Rakshith, Hanzo, Lajos   +2 more
core