Results 161 to 170 of about 1,536,819 (313)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Complexity and Efficiency in Repeated Games with Negotiation [PDF]

open access: yes
This paper considers the "negotiation game" (Busch and Wen, 1995) which combines the features of two-person alternating offers bargaining and repeated games.
Jihong Lee, Hamid Sabourian
core   +2 more sources

Improved meet-in-the-middle attack on ARIA cipher

open access: yesTongxin xuebao, 2015
A study on the structure of ARIA cipher is presented. A new 4-round distinguishing property for the meet-in-the-middle attack on ARIA cipher is presented by making use of the multiset and the truncated differential char-acteristic. The new distinguishing
Man-man LI, Shao-zhen CHEN
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Relation between Predictability and Complexity: Domestic and Public Consumption in the Romanian Economy [PDF]

open access: yes
We continue with the problem of the relation between predictability and complexity in the Romanian economy, analyzing other two components of GDP: domestic consumption and public consumption.
Saman, Corina   +2 more
core  

Understanding Decision‐Making to Tackle Complexity in Open Innovation Labs in Government

open access: yes
This article examines the decision‐making processes in open innovation labs (OI‐labs) in government. Through a qualitative single case study, we explore how the use of causal and effectual reasoning, as dichotomous logics, evolves over time and is ...
Leysen, Jan   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Algorithmic complexity theory and the relative efficiency of financial markets

open access: yes
Financial economists usually assess market efficiency in absolute terms. This is to be viewed as a shortcoming. One way of dealing with the relative efficiency of markets is to resort to the efficiency interpretation provided by algorithmic complexity ...
Giglio, Ricardo   +4 more
core  

Quaternion-based complexity study of human postural sway time series

open access: yes, 2009
A multidimensional approach for the study of the center of pressure (CoP) was selected. During the work the dataset was characterized recurring to algorithms taken from Chaotic and Stochastic time series analysis.
BRAVI, ANDREA
core  

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