Results 141 to 150 of about 1,536,819 (313)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Psychological Time: The effect of task complexity upon the human estimation of duration.
, 2007 The Appendix contains the raw data from all the experiments and a representative sample of the experimental software.This thesis was designed to investigate the effect of task complexity upon how humans estimate duration.
Webber, Simon
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Reconstruction of Optical Coherence Tomography Images from Wavelength Space Using Deep Learning
SensorsConventional Fourier domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into a wavenumber (k) domain to extract the depth profile.
Maryam Viqar +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Complexity Management for Composable Real-Time Systems
, 2006 Embedded real-time systems are becoming increasingly complex due to ever increasing size and functionality so that complexity management is of growing importance, especially in dependable hard real-time systems development where errors caused by ...
Rumpler, Bernhard
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Complexity and Efficiency in the Negotiation Game [PDF]
This paper considers the ``negotiation game'' Busch and Wen (1995)) which combines the features of two-person alternating offers bargaining and repeated games.
Jihong Lee, Hamid Sabourian
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
PREDICTABILITY AND COMPLEXITY IN MACROECONOMICS. THE CASE OF GROSS FIXED CAPITAL FORMATION IN THE ROMANIAN ECONOMY [PDF]
There is a relationship between predictability and complexity. The problem of evaluating the complexity of the macroeconomic phenomenon can be reduced to decomposition into its principal components (which may have, in their turn, a certain degree of ...
Saman, Corina +2 more
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