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Total Outer-Independent Domination Number: Bounds and Algorithms
AlgorithmsIn graph theory, the study of domination sets has garnered significant interest due to its applications in network design and analysis. Consider a graph G(V,E); a subset of its vertices is a total dominating set (TDS) if, for each x∈V(G), there exists an
Paul Bosch +3 more
doaj +1 more source
On the Complexity of Branching-Time Logics [PDF]
, 2009 We classify the complexity of the satisfiability problem for extensions of CTL and UB. The extensions we consider are Boolean combinations of path formulas, fairness properties, past modalities, and forgettable past. Our main result shows that satisfiability for CTL with all these extensions is still in 2-EXPTIME, which strongly contrasts with the ...
openaire +4 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
SensorsExisting secure data aggregation protocols are weaker to eliminate data redundancy and protect wireless sensor networks (WSNs). Only some existing approaches have solved this singular issue when aggregating data.
Samuel Kofi Erskine
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
An Algorithm for the Euclidean Bounded Multiple Traveling Salesman Problem
MathematicsIn the Bounded Multiple Traveling Salesman Problem (BMTSP), a tour for each salesman that starts and ends at the depot and respects the bounds on the number of cities that a feasible salesman tour should satisfy is constructed.
Víctor Pacheco-Valencia +3 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Center of Trapezoid Graph: Application in Selecting Center Location to Set up a Private Hospital
MathematicsThe central location problem is a key aspect of graph theory, with a significant importance in various applications and studies within the field. The center of a graph is made up of nodes that have the smallest eccentricity, where eccentricity is defined
Shaoli Nandi +5 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source