Results 111 to 120 of about 16,940,234 (305)
Approximating a Minimum Dominating Set by Purification
AlgorithmsA dominating set of a graph is a subset of vertices such that every vertex not in the subset has at least one neighbor within the subset. The corresponding optimization problem is known to be NP-hard.
Ernesto Parra Inza +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Rapid equivalent simplification algorithm for complex underground mine ventilation networks
Meitan xuebaoMine ventilation network equivalent simplification technology is a powerful tool for analyzing fluid networks. However, with the increasing number of tunnels in mine ventilation networks, their complexity also rises, challenging the precision and ...
Jinzhang JIA +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2019 Many great environmental challenges take the form of environmental public goods dilemmas, including climate change, water quality deterioration and biodiversity loss. There is a great need for comparative analysis of these challenges to inform the design
Hammond Wagner, Courtney Ryder
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Teaching public administrators and leaders to handle complexity [PDF]
, 2018 Understanding and working under complexity has become ‘the new normal’ in public administration. Hence complexity must also be integrated into teaching and training of public administrators, not only in higher education but also in in-service training ...
Vartiainen, Pirkko +4 more
core +1 more source
On the measurements of algorithms in big data era
大数据, 2016 The ability to store and analyze big data is a crucial capability of a powerful country in the new century.The current research of big data contains weakness on common scientific questions,general methodology,and theoretical analysis of real-time ...
Jialin ZHANG, Xiaoming SUN
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Entropy in Natural Time and the Associated Complexity Measures
, 2017 Natural time is a new time domain introduced in 2001. The analysis of time series associated with a complex system in natural time may provide useful information and may reveal properties that are usually hidden when studying the system in conventional ...
Sarlis, N.V., Nicholas Sarlis
core +1 more source