Results 91 to 100 of about 1,285,719 (263)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The T-DBSCAN Algorithm for Stopover Site Identification of Migration Birds Based on Satellite Positioning Data

open access: yesBiology
With the acceleration of social development and urbanization, birds’ natural habitats have been greatly disturbed and threatened. Satellite tracking technology can collect much bird activity data, providing important data support for habitat protection ...
Xinwu He   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Total Outer-Independent Domination Number: Bounds and Algorithms

open access: yesAlgorithms
In graph theory, the study of domination sets has garnered significant interest due to its applications in network design and analysis. Consider a graph G(V,E); a subset of its vertices is a total dominating set (TDS) if, for each x∈V(G), there exists an
Paul Bosch   +3 more
doaj   +1 more source

On the Complexity of Branching-Time Logics [PDF]

open access: yes, 2009
We classify the complexity of the satisfiability problem for extensions of CTL and UB. The extensions we consider are Boolean combinations of path formulas, fairness properties, past modalities, and forgettable past. Our main result shows that satisfiability for CTL with all these extensions is still in 2-EXPTIME, which strongly contrasts with the ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Secure Data Aggregation Using Authentication and Authorization for Privacy Preservation in Wireless Sensor Networks

open access: yesSensors
Existing secure data aggregation protocols are weaker to eliminate data redundancy and protect wireless sensor networks (WSNs). Only some existing approaches have solved this singular issue when aggregating data.
Samuel Kofi Erskine
doaj   +1 more source

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