Results 91 to 100 of about 1,285,719 (263)
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
With the acceleration of social development and urbanization, birds’ natural habitats have been greatly disturbed and threatened. Satellite tracking technology can collect much bird activity data, providing important data support for habitat protection ...
Xinwu He +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Total Outer-Independent Domination Number: Bounds and Algorithms
In graph theory, the study of domination sets has garnered significant interest due to its applications in network design and analysis. Consider a graph G(V,E); a subset of its vertices is a total dominating set (TDS) if, for each x∈V(G), there exists an
Paul Bosch +3 more
doaj +1 more source
On the Complexity of Branching-Time Logics [PDF]
We classify the complexity of the satisfiability problem for extensions of CTL and UB. The extensions we consider are Boolean combinations of path formulas, fairness properties, past modalities, and forgettable past. Our main result shows that satisfiability for CTL with all these extensions is still in 2-EXPTIME, which strongly contrasts with the ...
openaire +2 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Existing secure data aggregation protocols are weaker to eliminate data redundancy and protect wireless sensor networks (WSNs). Only some existing approaches have solved this singular issue when aggregating data.
Samuel Kofi Erskine
doaj +1 more source

