Results 81 to 90 of about 1,536,819 (313)

Entropy in Natural Time and the Associated Complexity Measures

, 2017
Natural time is a new time domain introduced in 2001. The analysis of time series associated with a complex system in natural time may provide useful information and may reveal properties that are usually hidden when studying the system in conventional ...
Sarlis, N.V., Nicholas Sarlis
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Leveraging Metaheuristics for Feature Selection With Machine Learning Classification for Malicious Packet Detection in Computer Networks

IEEE Access
Robust Intrusion Detection Systems (IDS) are increasingly necessary in the age of big data due to the growing volume, velocity, and variety of data generated by modern networks.
Aganith Shanbhag, Shweta Vincent, S. B. Bore Gowda, Om Prakash Kumar, Sharmila Anand John Francis   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Responsive Governance and Harmful Microbial Blooms on Lake Erie: An ABM Approach

, 2019
In general, decision makers tend to respond to problems rather than prevent them. In political science, this process of responsive governance is associated with complex dynamics such as availability cascades and punctuated equilibrium.
Pavlovich, Tyler, Webster, DG
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Complexity Analysis of Spontaneous Brain Activity in Attention-Deficit/Hyperactivity Disorder: Diagnostic Implications

, 2009
Background: Attention-deficit/hyperactivity disorder (ADHD) is defined as the most common neurobehavioral disorder of childhood, but an objective diagnostic test is not available yet to date.
Biederman, Joseph, García Campos, Natalia, Fernandez, Alberto, Navas, Marta, Escudero, Javier; id_orcid, Gomez, Carlos, Hornero, Roberto, Ortiz, Tomas, Garcia-Campos, Natalia, Zuluaga Arias, María del Pilar, Escudero, Javier, Quintero, Javier, Zuluaga, Pilar   +12 more
core   +1 more source

New related-key rectangle attack on 42-round SHACAL-2

Tongxin xuebao, 2009
A new 34-round related-key rectangle distinguisher was constructed by exploiting the properties of the round transform of SHACAL-2. Moreover, two new relate-key rectangle attacks on 40-round and 42-round reduced SHACAL-2 were presented by using both the ...
WEI Yong-zhuang1, 2
doaj  

A novel and efficient approach for line segment clipping against a convex polygon

Ruhuna Journal of Science, 2019
This paper proposes a new line clipping algorithm against a convex polygon with 𝑂(𝑁) time complexity. The line segment is pruned against each extended edge of the polygon as the first step of the proposed algorithm.
K. R. Wijeweera, S. R. Kodituwakku, M. A. P. Chamikara   +2 more
doaj   +1 more source