Results 241 to 250 of about 22,856,606 (379)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Scope of Message Planning: Evidence From Production of Sentences With Heavy Sentence-Final NPs. [PDF]

Cogn Sci
Konopka AE.
europepmc   +1 more source

Reducing the time complexity of testing for local threshold testability

, 2004
A. N. Trahtman
openalex   +1 more source

Reducing the Time Complexity of the Derandomized Evolution Strategy with Covariance Matrix Adaptation (CMA-ES)

Evolutionary Computation, 2003
Nikolaus Hansen, Sibylle D. Müller, P. Koumoutsakos   +2 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

On Synchronous Robotic Networks—Part II: Time Complexity of Rendezvous and Deployment Algorithms [PDF]

, 2007
Sonia Martı́nez, Francesco Bullo, Jorge Cortés, Emilio Frazzoli   +3 more
openalex   +1 more source

Understanding the tumor immune microenvironment (TIME) for effective therapy

Nature Network Boston, 2018
M. Binnewies, Edward W. Roberts, K. Kersten, Vincent Chan, Douglas Fearon, M. Merad, L. Coussens, D. Gabrilovich, S. Ostrand-Rosenberg, S. Ostrand-Rosenberg, C. Hedrick, R. Vonderheide, M. Pittet, R. Jain, W. Zou, T. Howcroft, E. Woodhouse, R. Weinberg, M. Krummel   +18 more
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Temporal complexity of terrestrial ecosystem functioning and its drivers. [PDF]

Nat Commun
Fernández-Martínez M, Janssens IA, Obersteiner M, Manning P, Andrade FM, Rodríguez-Penedo E, Peñuelas J.   +6 more
europepmc   +1 more source

Hash sort: A linear time complexity multiple-dimensional sort algorithm

, 2004
William F. Gilreath
openalex   +2 more sources