Results 101 to 110 of about 7,849,772 (280)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Level Reduction of Output Noise of Reference Voltage Sources
Acta Technologica Agriculturae, 2018 Technologies for processing of digital signals find broad application in all spheres of the human activity, including agriculture. Further perfecting of these technologies is related to increasing of resolving power in analogue-to-digital and digital-to ...
Bondar Sergey +4 more
doaj +1 more source
Phasefronts as surfaces of constant vertex time [PDF]
EPJ Web of ConferencesIn the geometric optics approximation typical of far fields (vanishing wavelength), wavefronts emerge as constant eikonal surfaces. The electric (E) and magnetic (H) field vectors are mutually perpendicular and tangent to the wavefront.
Muschaweck Julius, Vos Willem L.
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A Critical Analysis of the Thermo-Optic Time Constant in Si Photonic Devices
PhotonicsThe use of integrated heaters is widespread in silicon photonics for waveguide temperature control. The dynamical behavior of the heaters is important for determining their usefulness for certain applications.
David Coenen +4 more
doaj +1 more source
New method for determining time constant of resistors. [PDF]
Rev Sci Instrum, 2023 Wang Y +3 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Constant Space and Non-Constant Time in Distributed Computing
, 2017 While the relationship of time and space is an established topic in traditional centralised complexity theory, this is not the case in distributed computing. We aim to remedy this by studying the time and space complexity of algorithms in a weak message-passing model of distributed computing.
Suomela Jukka, Lempiäinen Tuomo
openaire +5 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source