Results 81 to 90 of about 442,244 (267)

Mathematical model on influence of past experiences on present activities of human brain

Computational and Mathematical Biophysics
This article explores how emotional feelings linked to stored memories of past experiences influence the present activity of the human brain. To analyse this, a mathematical model is considered describing the dynamics in a two-layered network in which ...
Rao P. Raja Sekhara, Ratnam K. Venkata, Shirisha G.   +2 more
doaj   +1 more source

Reliability Modeling of Systems with Undetected Degradation Considering Time Delays, Self-Repair, and Random Operating Environments

Mathematics
In some settings, systems may not fail completely but instead undergo performance degradation, leading to reduced efficiency. A significant concern arises when a system transitions into a degraded state without immediate detection, with the degradation ...
Hoang Pham
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

An Effective Hybrid Cuckoo Search Algorithm for Unknown Parameters and Time Delays Estimation of Chaotic Systems

IEEE Access, 2018
Parameter estimation is an important issue in nonlinear science, which can be formulated as a multi-dimensional problem. Numbers of nature-inspired meta-heuristic algorithms have been applied for parameter estimation of chaotic systems; however, many of ...
Jiamin Wei, Yongguang Yu
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Comprehensive Predictive Control Method for Automated Vehicles With Delays

IEEE Access, 2019
This paper considers the control problem of automated vehicles with delays. We develop a comprehensive control method within the framework of model predictive control (MPC) with compensation for the input delay and the state delay for automated vehicles ...
Wei Liu, Zhiheng Li
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Relative approximate controllability of fractional stochastic delay evolution equations with nonlocal conditions

Le Matematiche, 2014
In this paper, we study the relative approximate controllability of nonlinear fractional stochastic evolution equations with time delays and nonlocal conditions, in Hilbert space, via new fixed point analysis approach.
Toufik Guendouzi
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source