Results 31 to 40 of about 15,433,823 (259)

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess   +5 more
wiley   +1 more source

Speech/Music Discrimination: Novel Features in Time Domain [PDF]

open access: yes, 2010
This research aimed to find novel features that can be used to discriminate between speech and music in the time domain for the purpose of data retrieval.
Alnadabi, Muhammad Saeid Muhammad   +1 more
core  

Time Pickoff Method Using Dual-Edge Discrimination to Mitigate Time Walk

open access: yesIEEE Access
Precise generation of a timing pulse at the signal is crucial for high-resolution time measurements, accomplished using a time pickoff circuit. The primary challenge in time pickoff circuits is to minimize the dependency of timing pulse generation on ...
Jeong Hun Shin   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Temporal discrimination of sub- and suprasecond time intervals: a voxel-based lesion mapping analysis

open access: yesFrontiers in Integrative Neuroscience, 2011
We used voxel-based lesion-symptom mapping (VLSM) to determine which brain areas are necessary for discriminating time intervals above and below one second.
Cynthia M Gooch   +3 more
doaj   +1 more source

Improvement of Secondary Task (Discrimination Reaction Time), Due to Motivational Self-Talk [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2015
The self-talk is one of psychological interventions that can be effective on improving and success in the motor performance and sport performance. So, the aim of the present study was to investigation effectiveness the motivational self-talkon secondary ...
Nastaran Naderi Rad, Shahzad Tahmasebi
doaj   +1 more source

Research progress of organic scintillators for neutron detection

open access: yesHe jishu, 2023
During the neutron detection process, owing to the effects of inelastic scattering and slow neutron capture, a neutron-gamma mixed radiation field is formed, which increases the complexity of neutron detection.
HU Wanping   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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