Results 81 to 90 of about 6,163,357 (346)

Time Domain Explorations With Digital Sky Surveys [PDF]

, 2004
One of the new frontiers of astronomical research is the exploration of time variability on the sky at different wavelengths and flux levels. We have carried out a pilot project using DPOSS data to study strong variables and transients, and are now ...
Andrews, P., Baltay, C., Bauer, A., Bogosavljevic, M., Brunner, R., Djorgovski, S. G., Duffau, S., Ellman, N., Gebhard, M., Graham, M. J., Granett, B., Jerke, J., Kollipara, P., Krause, E., Mahabal, A. A., Mufson, S., Musser, J., Rabinowitz, D., Rengstorf, A., Williams, R.   +19 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Time Domain Simplified Equations and its Iterative Calculation Model for LLC Resonant Converter

IEEE Access, 2020
LLC resonant converters can achieve soft switching and loss reduction. However, the analysis methods of wide frequency range LLC converters generally have problems with incomplete working condition analysis at non-resonant frequencies and there is always
Jingkai Niu, Yibing Tong, Qing Ding, Xuezhi Wu, Xiaomin Xin, Xin Wang   +5 more
doaj   +1 more source

Gauge techniques in time and frequency domain TLM

, 2009
Typical features of the Transmission Line Matrix (TLM) algorithm in connection with stub loading techniques and prone to be hidden in common frequency domain formulations are elucidated within the propagator approach to TLM.
Cap, Christopoulos, De Cogan, De Cogan, Hein, Hein, Hein, Hein, Hoefer, Johns, Lax, Mandl, Steffen Hein, Witwit   +13 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Spectral domain OCT versus time domain OCT in the evaluation of macular features related to wet age-related macular degeneration

Clinical Ophthalmology, 2012
Luisa Pierro1, Elena Zampedri1, Paolo Milani2, Marco Gagliardi1, Vincenzo Isola2, Alfredo Pece21Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, Milano, Italy, 2Fondazione Retina 3000, Milano, ItalyBackground: The ...
Isola V, Gagliardi M, Milani P, Zampedri E, Pierro L, Pece A   +5 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Identifying Mechanical Properties of Viscoelastic Materials in Time Domain Using the Fractional Zener Model

Latin American Journal of Solids and Structures
The present paper aims at presenting a methodology for characterizing viscoelastic materials in time domain, taking into account the fractional Zener constitutive model and the influence of temperature through Williams, Landel, and Ferry’s model. To that
Ana Paula Delowski Ciniello, Carlos Alberto Bavastri, Jucélio Tomás Pereira   +2 more
doaj   +1 more source

TIME Domain Analysis of Sound Signals for Bearing Damage Identification [PDF]

, 2014
Time domain analysis requires less computational time compared to the frequency domain. Analysis is performed directly on the signal without any conversion at all.
Aswin, M. (Muhammad), Irawan, Y. S. (Yudy), Suyono, H. (Hadi), Wardana, I. (ING)   +3 more
core