Results 81 to 90 of about 5,371,151 (345)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Time Domain Explorations With Digital Sky Surveys [PDF]

open access: yes, 2004
One of the new frontiers of astronomical research is the exploration of time variability on the sky at different wavelengths and flux levels. We have carried out a pilot project using DPOSS data to study strong variables and transients, and are now ...
Andrews, P.   +19 more
core   +2 more sources

The Future of X-ray Time Domain Surveys

open access: yes, 2012
Modern X-ray observatories yield unique insight into the astrophysical time domain. Each X-ray photon can be assigned an arrival time, an energy and a sky position, yielding sensitive, energy-dependent light curves and enabling time-resolved spectra down
Haggard, Daryl, Sivakoff, Gregory R.
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Time Domain Simplified Equations and its Iterative Calculation Model for LLC Resonant Converter

open access: yesIEEE Access, 2020
LLC resonant converters can achieve soft switching and loss reduction. However, the analysis methods of wide frequency range LLC converters generally have problems with incomplete working condition analysis at non-resonant frequencies and there is always
Jingkai Niu   +5 more
doaj   +1 more source

TasNet: time-domain audio separation network for real-time, single-channel speech separation

open access: yes, 2018
Robust speech processing in multi-talker environments requires effective speech separation. Recent deep learning systems have made significant progress toward solving this problem, yet it remains challenging particularly in real-time, short latency ...
Luo, Yi, Mesgarani, Nima
core   +1 more source

Magnetic field distribution of silver blood cancer with finite difference time domain (FDTD) simulation [PDF]

open access: bronze, 2021
Vinda Zakiyatuz Zulfa   +6 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Spectral domain OCT versus time domain OCT in the evaluation of macular features related to wet age-related macular degeneration

open access: yesClinical Ophthalmology, 2012
Luisa Pierro1, Elena Zampedri1, Paolo Milani2, Marco Gagliardi1, Vincenzo Isola2, Alfredo Pece21Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, Milano, Italy, 2Fondazione Retina 3000, Milano, ItalyBackground: The ...
Isola V   +5 more
doaj  

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