A nonparametric dimension test of the term structure [PDF]
This paper addresses the problem of conducting a nonparametric test of the dimension of the state variable vector in a continuous-time term structure model.
Gil-Bazo, Javier, Rubio, Gonzalo
core +1 more source
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran+6 more
wiley +1 more source
Determining Factors of Czech Foreign Trade: A Cross-Section Time Series Perspective [PDF]
By quantifying the determining factors of Czech trade during 1993-2002, this paper enriches the empirical trade literature with evidence from an economy that has undergone intensive structural changes.
Jiri Podpiera+2 more
core
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke+2 more
wiley +1 more source
Time to diagnosis and factors affecting diagnostic delay in amyotrophic lateral sclerosis
Danielle Richards, J. Morren, E. Pioro
semanticscholar +1 more source
Estimation of Dynamic Mixed Double Factors Model in High Dimensional Panel Data [PDF]
The purpose of this article is to develop the dimension reduction techniques in panel data analysis when the number of individuals and indicators is large.
Chen, Kani, Fang, Guobin, Zhang, Bo
core
A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Improving the predictability of take-off times with Machine Learning : a case study for the Maastricht upper area control centre area of responsibility [PDF]
The uncertainty of the take-off time is a major contribution to the loss of trajectory predictability. At present, the Estimated Take-Off Time (ETOT) for each individual flight is extracted from the Enhanced Traffic Flow Management System (ETFMS ...
Ballerini, Franck+4 more
core
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer+10 more
wiley +1 more source
School- and Leisure Time Factors Are Associated With Sitting Time of German and Irish Children and Adolescents During School: Results of a DEDIPAC Feasibility Study. [PDF]
Lubasch JS+12 more
europepmc +1 more source