Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Time-Frequency Analysis of Muscle Activation Patterns during the Instep Kick in Elite and Amateur Soccer Players. [PDF]
Zhu J +11 more
europepmc +1 more source
A Time-Frequency Analysis of the Coherences of the US Business [PDF]
The dating of a possible European business cycle has been inconclusive. At this stage, there is no consensus on the existence of such a cycle, or of its periodicity and amplitude, or of the relationship of individual member countries to that cycle.
Christian Richter, Andrew Hughes Hallett
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Lightweight deep learning model for nonconvulsive status epilepticus diagnosis using EEG time-frequency analysis. [PDF]
Xu D +6 more
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Proton Nuclear Magnetic Resonance With Time-Frequency Analysis: A Potential Diagnostic Approach for Keloids. [PDF]
Xia G +10 more
europepmc +1 more source
Adaptive Approach to Time-Frequency Analysis of AE Signals of Rocks. [PDF]
Lukovenkova O +2 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Experimental Study on Time-Frequency Analysis of Vibration Signals from an Active De-Icing Exciter on Transmission Lines. [PDF]
Fan D, Zhao B, Li M, Wang H, Ding L.
europepmc +1 more source

