Results 161 to 170 of about 6,746,316 (343)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Time-Frequency Analysis of ERG With Discrete Wavelet Transform and Matching Pursuits for Glaucoma. [PDF]

Transl Vis Sci Technol, 2022
Sarossy M, Crowston J, Kumar D, Weymouth A, Wu Z.   +4 more
europepmc   +1 more source

Wavelet analysis of molecular dynamics: Efficient extraction of time-frequency information in ultrafast optical processes [PDF]

, 2013
Javier Prior, Enrique Castro, Alex W. Chin, J. R. L. de Almeida, Susana F. Huelga, Martin B. Plenio   +5 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Enhancing Time-Frequency Analysis with Zero-Mean Preprocessing. [PDF]

Sensors (Basel), 2022
Jin S, Johansson P, Kim H, Hong S.
europepmc   +1 more source

New method for nonlinear seismic analysis in time domain using frequency analysis with superposition of pulse waves

, 2016
Hideaki NAGASAKA, Yoshihito Tanaka, Ho Cho   +2 more
openalex   +2 more sources

Time-frequency Analysis of Electroencephalogram Signals in a Perceptual Decision-Making Task of Random Dot Kinematograms

, 2022
Alireza Ettefagh, Farnaz Ghassemi, Zahra Tabanfar   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Cortical activity during the wind-up of flexion reflex and pain: a magnetoencephalographic study using time-frequency analysis. [PDF]

Cereb Cortex, 2023
Taniguchi T, Kinukawa TA, Takeuchi N, Sugiyama S, Nishihara M, Kida T, Nishiwaki K, Inui K.   +7 more
europepmc   +1 more source

Frequency and Time Domain Analysis of Foetal Heart Rate Variability with Traditional Indexes: A Critical Survey [PDF]

, 2016
Maria Romano, Luigi Iuppariello, Alfonso Maria Ponsiglione, Giovanni Improta, Paolo Bifulco, Mario Cesarelli   +5 more
openalex   +1 more source