Results 181 to 190 of about 6,746,316 (343)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Time-frequency analysis methods and their application in developmental EEG data. [PDF]
Morales S, Bowers ME.
europepmc +1 more source
Multichannel frequency and time-frequency analysis [PDF]
Koenig, T, Pascual-Marqui, R D
openaire +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Wake-Independent Velocity Estimation and Motion Compensation for SAR Moving Target Based on Time-Frequency Analysis. [PDF]
Wen C +6 more
europepmc +1 more source
Spectra in low-rank localized layers (SpeLLL) for interpretable time-frequency analysis. [PDF]
Tuft M, Hall MH, Krafty RT.
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Unveiling Turbulence-Induced Stress Dynamics in Dented Pipe Using Acoustic Emission and Time-Frequency Analysis. [PDF]
Firdaus SM +3 more
europepmc +1 more source

