Results 71 to 80 of about 37,062,975 (290)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Multi component Radar Emitter Signal Detection Based on S-method
:When the conventional time frequency methods are applied to process multi component radar emitter signals, they have many cross terms, and cannot detect time domain parameters of each signal component and difficultly process signals in low signal to ...
doaj
Adaptive noise cancelling and time–frequency techniques for rail surface defect detection [PDF]
Adaptive noise cancelling (ANC) is a technique which is very effective to remove additive noises from the contaminated signals. It has been widely used in the fields of telecommunication, radar and sonar signal processing.
Liang, B. +11 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Approximation of Time-Frequency Shift Equivariant Maps by Neural Networks
Based on finite-dimensional time-frequency analysis, we study the properties of time-frequency shift equivariant maps that are generally nonlinear. We first establish a one-to-one correspondence between Λ-equivariant maps and certain phase-homogeneous ...
Dae Gwan Lee
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A Time–Frequency Domain Analysis Method for Variable Frequency Hopping Signal
A variable frequency hopping (VFH) signal is a kind of frequency hopping (FH) signal that varies both in frequency and dwell time. However, in radio surveillance, the existing methods for unidentified signals using VFH cannot be effectively handled.
Zhengzhi Zeng +3 more
doaj +1 more source
Time–frequency analysis of bivariate signals
Many phenomena are described by bivariate signals or bidimensional vectors in applications ranging from radar to EEG, optics and oceanography. The time-frequency analysis of bivariate signals is usually carried out by analyzing two separate quantities, e.g. rotary components.
Flamant, Julien +2 more
openaire +5 more sources

