Results 101 to 110 of about 9,112,332 (303)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Building with Time, History, and Resilience at Yale

open access: yesArchitectural Histories, 2019
This article examines Louis Kahn’s design for the New Yale Art Gallery as an exemplar of ‘building-in-time.’ The novel design breaks formally with then modernist-free architecture of the Yale campus, and yet complements and completes the existing ...
Marvin Trachtenberg
doaj   +1 more source

Phyllonorycter messaniella (Zeller, 1846), new record for the Maltese Islands (Lepidoptera: Gracillariidae) [PDF]

open access: yes, 2008
Phyllonorycter messaniella is recorded for the first time from the Maltese Islands.
Mifsud, David, Sammut, Paul
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Evidence-based history taking under "time constraint"

open access: yesJournal of Research in Medical Sciences, 2011
Physicians all through the world visit patients under time limitations. The most important troubled clinical skill under "time constraint" is the diagnostic approach. In this situation, clinicians need some diagnostic approaches to reduce both diagnostic
Alireza Moayyeri   +3 more
doaj  

A brief history of medical uniforms: from ancient history to the COVID-19 time

open access: yesRevista do Colégio Brasileiro de Cirurgiões
Medical Uniforms date back from medieval times. Nursing uniforms were based on nuns clothes whereas doctors used the famous “plague costumes” and black “frock” coats from about 15th to early 19th century.
VICTORIA RODRIGUES O’DONNELL   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Graph time: content History or Mathematics?

open access: yesRevista MENDIVE, 2009
In teaching of History at the school, for the temporary location of the fats that are studied, is used a straight representation: a straight line o r half straight line (number ray).
Víctor José Hernández Rodríguez   +2 more
doaj  

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