Results 121 to 130 of about 9,161,606 (303)
On the Cultural History of Time Series Graphs
Zeitschrift für digitale GeisteswissenschaftenTaking the insights from diagrammatology – rooting in German media and culture studies (Medienkulturwissenschaft) and semiology – as background, this essay seeks to answer the question of how the history of the visual representation of temporal processes
Botond Szemes
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Time and History in Hegel’s Phenomenology of Spirit [PDF]
Ideas y Valores, 2007 Resumen:En este artículo se presenta una interpretación de las tesis fundamentales de Hegel en la Fenomenología del Espíritu acerca de la relación entre tiempo, historia y filosofía especulativa o ciencia.
Luis Mariano De La Maza
doaj
Time, History, and Philosophy of History
Journal of the Philosophy of History, 2014 In this paper, I intend to show that different ways of describing, representing or thinking about human affairs presuppose different types of consciousness of temporality. This proposal is embedded in the fruitful concept ‘régimes d’historicités’, which was coined by F. Hartog.
openaire +2 more sources
Online Movement Correlation of Wireless Sensor Nodes [PDF]
, 2007 Sensor nodes can autonomously form ad-hoc groups based on their common context. We propose a solution for grouping sensor nodes attached on the same vehicles on wheels.
Havinga, P.J.M. +3 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Time Blocks Decomposition of Multistage Stochastic Optimization Problems
, 2018 Multistage stochastic optimization problems are, by essence, complex because their solutions are indexed both by stages (time) and by uncertainties (scenarios). Their large scale nature makes decomposition methods appealing.The most common approaches are
Carpentier, Pierre +3 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source