Results 141 to 150 of about 3,293,193 (265)

Excerpt, Oral History Interview, Michiko Tashiro

open access: yes, 2019
Excerpt, summary, and index of an oral history interview of Michiko Tashiro. Conducted and recorded by Claudia Katayanagi on July 23, 2019, at the MIS Historic Learning Center in San Francisco, CA.
Michiko Tashiro, Claudia Katayanagi
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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Excerpt, Oral History Interview, Sadako Nimura Kashiwagi

open access: yes, 2019
Excerpt, summary, and index of an oral history interview of Sadako Nimura Kashiwagi. Conducted and recorded by Claudia Katayanagi on July 23, 2019, at the MIS Historic Learning Center in San Francisco, CA.
Sadako Nimura Kashiwagi   +1 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Excerpt, Oral History Interview, Harumi Serata

open access: yes, 2019
Excerpt, summary, and index of an oral history interview of Lawson Ichiro Sakai. Conducted and recorded by Claudia Katayanagi on June 14, 2019, at the MIS Historic Learning Center in San Francisco, CA.
Claudia Katayanagi, Harumi Serata
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Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Excerpt, Oral History Interview, Jeannette Arakawa

open access: yes, 2019
Excerpt, summary, and index of an oral history interview of Jeannette Arakawa. Conducted and recorded by Claudia Katayanagi on April 13, 2019, at the MIS Historic Learning Center in San Francisco, CA.
Claudia Katayanagi, Jeannette Arakawa
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Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Excerpt, Oral History Interview, George Omi

open access: yes, 2019
Excerpt, summary, and index of an oral history interview of George Omi. Conducted and recorded by Claudia Katayanagi on June 13, 2019, at the MIS Historic Learning Center in San Francisco, CA.
George Omi, Claudia Katayanagi
core  

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