Results 71 to 80 of about 3,293,193 (265)
FRENCH EUROSCEPTICISM: HISTORY AND THE PRESENT TIME
Контуры глобальных трансформаций: политика, экономика, право, 2017 The phenomena of euroscepticism in France is analyzed in the paper. The participation of France in key projects of the European construction is examined.
P. P. Timofeev
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Sculpting History: A Formal Analysis of Michael Stevenson's *The Fountain of Prosperity* (2006)
Index JournalArt historian Amy Knight Powell has suggested that a key characteristic of form is its temporal “promiscuity.” Reliably unfaithful to its original moment, form is open to de- and re-contextualisation: as it enters into different settings and new liaisons
Anna Parlane
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Battle flags hanging in Ohio History Center plaza
, 1970 Photograph of Ohio's Battle Flag collection hanging in the plaza of the Ohio History Center in Columbus, Ohio, ca. 1970. The flags were displayed on the Center’s plaza level from the time the building opened in 1970 through the late 1980s, when they were
Ohio History Connection
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Time, Collingwood, Wittgenstein and Possible Worlds in Alternate History and History-therapy [PDF]
تاریخ نگری و تاریخ نگاریTime and its dimensions are a much-discussed topic among scholars. The examination of the technical and expertise aspects of time in postmodern discourse has led to diverse reactions.
Morteza Nouraei +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Time frames. Negotiating Cultural History
, 2015 Time Frames brings together a group of cultural historians studying several different periods and locations in the history of Western culture, to discuss the temporal structures which historical studies live by.
Tuohela, Kirsi (toim.), Korhonen, Anu
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