Results 61 to 70 of about 3,293,193 (265)
Uncovering the Forgotten Roots of Digital History: the Association for History and Computing
, 2023 In recent years, scholars have started to investigate the diverse genealogies of the digital humanities, as part of efforts to consolidate the field by excavating its historical and intellectual underpinnings.
ZAAGSMA, Gerben
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Problem of time in Hegel's philosophy of history [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-Graduação em Filosofia, Florianópolis, 2010O objetivo deste trabalho é mostrar porque o problema do tempo é o calcanhar de Aquiles no ...
Altman, William Henry Furness
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TIME LINE OF HISTORY OF HYPERTENSION TREATMENT
Frontiers in Cardiovascular Medicine, 2016 It is surprising that only about 50 years ago hypertension was considered an essential malady and not a treatable condition. Introduction of thiazide diuretics in late 50’s made some headway in successful treatment of hypertension and ambitious ...
Mohammad Golam Saklayen +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Against the Fetishisation of Plural Time [PDF]
It has become an unflinching belief that time is plural and temporal multiplicity is the best framework to study the relationship between time and society.
Sinha, Nitin
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Teaching the History of Tracking Time with Technology
Journal of Mathematics Education at Teachers College, 2016 This article focuses on the mathematical value of teaching angles through the use of sundials in the classroom. The history of sundials and the mathematics embedded within them is discussed in detail.
Margaret Fitz
doaj +3 more sources
Index JournalThis paper focuses on the work of Indonesian multidisciplinary art group, Papermoon Puppet Theatre and its performance, *Mwathirika* (2010), a powerful contemporary representation of the injustice buried within established historical narratives and its ...
Kate O'Connor
doaj +1 more source